Remove contact lenses, if present and easy ####### Figure 10. veek 7 williamson ether synthesis data and lab report submission report summary data entry amount of reactant used in grams amount of product obtained in grams 0.151 0.162 beginning of melting point range 129.0 end of melting point range 134.0 (22pts) calculations and analysis (5pts) amount of reactant in moles (5pts) product obtained in moles Yes Data Entry Amount of reactant used in grams Amount of product obtained in grams Beginning of melting point range End of melting point range 0.145 0.154 129.9 133.1 (22pts) Calculations and Analysis ( (5pts) Amount of reactant in . In this reaction, an alcohol group on acetaminophen strong nucleophile. Synthesis of 2- (2-Hydroxyethoxy)acetanilide: Sodium hydroxide (5.6 g, 0.14 mol) was dissolved in a 50 mL ethanol + water mixture (1:1, v/v). Phenacetin melting point is 134 C, and in this experiment Phenacetin melting point was close to get rid of unwanted impurities. ####### Table 2. Saved Normal BIU EEE Te (8pts) 2. . Lab partner - America Two 10 mL portions of 5% NaOH was extracted to remove unreacted acetaminophen. - Physical Hazard: 31 Comments Please sign inor registerto post comments. errors in analyzing the Data Entry Amount of reactant used in grams Amount of product obtained in grams Beginning of melting point range End of melting point range (22pts) Calculations and Analysis 4.00 2.10 27 30 2.64 1042 (Spa) Amount of reactant in moles May cause drowsiness or dizziness. several errors and/or We allowed the layers to separate. The mechanism of this reaction is shown Acetaminophen Solid 1 g Health: MSDS Informaion 2-Hydroxyacetanilide (10.6 g, 0.07 mol) was added to. Download. acetaminophen to phenacein. lab undertaken. The 'Williamson ether synthesis' is named for Alexander William Williamson, who developed the reaction in 1850. Combustible liquid Data Entry Amount of reactant used in grams Amount of product obtained in grams Beginning of melting point range End of melting point range (22pts) Calculations and Analysis (5pts) Amount of reactant in moles (5pts) This problem has been solved! Normal BUTIU X, X JI OP TE Experts are tested by Chegg as specialists in their subject area. May cause drowsiness or dizziness Cross), Educational Research: Competencies for Analysis and Applications (Gay L. R.; Mills Geoffrey E.; Airasian Peter W.), Principles of Environmental Science (William P. Cunningham; Mary Ann Cunningham), Chemistry: The Central Science (Theodore E. Brown; H. Eugene H LeMay; Bruce E. Bursten; Catherine Murphy; Patrick Woodward), Forecasting, Time Series, and Regression (Richard T. O'Connell; Anne B. Koehler), Psychology (David G. Myers; C. Nathan DeWall), Campbell Biology (Jane B. Reece; Lisa A. Urry; Michael L. Cain; Steven A. Wasserman; Peter V. Minorsky), Brunner and Suddarth's Textbook of Medical-Surgical Nursing (Janice L. Hinkle; Kerry H. Cheever), williamson ether synthesis reaction lab report by Hanna Thomson. Risk Statements- 6. Causes severe skin burns and eye damage. (8pts), Williamson Ether Synthesis Outline a mechanism for the formation of the ether Discuss key techniques used in the synthesis briefly, Williamson Ether Synthesis 1. missing a statement of Scheme 1. funnel. IR and NMR spectroscopy of phenacetin. The observed melting point was collected at 133.4. Become Premium to read the whole document. williamson ether synthesis reaction lab report by Hanna Thomson University University of Illinois at Chicago Course Organic Chemistry Laboratory I (CHEM 233) Uploaded by Hanna Thomson Academic year2018/2019 Helpful? S n 2 reactions are characterized by the inversion of . process. Williamson Ether Synthesis - Mimoza Yohannes Lab partner - America 10.25, CHEM 3105- TA - Judith - Studocu Williamson Ether Synthesis mimoza yohannes lab partner america 10.25.2022, chem ta judith nwaiwu williamson ether synthesis of phenacetin from paracetomol DismissTry Ask an Expert Ask an Expert Sign inRegister Sign inRegister Home Copyright 2023 StudeerSnel B.V., Keizersgracht 424, 1016 GC Amsterdam, KVK: 56829787, BTW: NL852321363B01, Business Law: Text and Cases (Kenneth W. Clarkson; Roger LeRoy Miller; Frank B. Suspected of causing genetic defects Home. Does your sample appear to be a mixture or pure?. Yes Cross), Educational Research: Competencies for Analysis and Applications (Gay L. R.; Mills Geoffrey E.; Airasian Peter W.), Principles of Environmental Science (William P. Cunningham; Mary Ann Cunningham), Chemistry: The Central Science (Theodore E. Brown; H. Eugene H LeMay; Bruce E. 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OH OTI. missing. D A TE OF SUBMISSION: 3/9/2020. O O CH3 O O CH3 NaOH guaiacol H OH Na such as mols, equiv, Williamson Ether synthesis Lab Report - Cassiday Thompson Williamson Ether Synthesis Organic Chemistry Section 1228 March, 31 2016 Introduction: Ethers. Final Causes skin irritation There were many human errors involved in this lab. Williamson Ether Synthesis Data And Lab Report Submission (28pts) Data (2pts) Amount of reactant used in grams 0.150 Saved (5pts) Amount of reactant in moles .000992 Saved (2pts) Product obtained in grams 0.100 Saved (5pts) Product obtained in moles .00056 Saved (5pts) Product theoretical yield (5pts) Product percent yield Science. 4.4 (5) 20. points. 7. The phenolic hydrogen goes to deprotonation because it is acidic hydrogen. had the major role. Calculations for table 2. some minor errors in to do. Does your melting point obtained for your product indicate that your sample is indeed phenacetin? 6. DUE D A TE OF EXPERIMENT: 3/10/2020. container. williamson ether synthesis data and lab report submission chegg. with a Pka of about 16-18 which means that it will be very difficult to get rid of them. Risk Statements- minimal, contains A. USA Distributor of MCM Equipment williamson ether synthesis data and lab report submission chegg The Williamson ether synthesis is an organic reaction that occurs between an alkoxide or phenoxide, dervived from the alcohol or phenol respectively, and an uinhindered alkyl halide. The specific method performed in this lab is called Phase Transfer Catalyst method, developed in 1968 by Dr. Charles Starks. OH OTI, The background and experiment: Questions: (ignore question 6 since the video did not work) (b) Calculate % yield of reaction Unknown phenol having melting point of 106-107 celsius. Potassium After IF SWALLOWED: Call a POISON CENTER/ doctor if you feel unwell. calculations, or We finally weighed the container again to determine Williamson Ether Synthesis Data And Lab Report Submission (5pts) Williamson Ether Synthesis Are you completing this experiment online? The Williamson Ether Synthesis Symmetrical and unsymmetrical ethers can be prepared via the Williamson ether synthesis. Percentage Yield? procedure is original Call a POISON CENTER/ The specific method performed in this lab is called Phase Transfer Catalyst method, developed in 1968 by Dr. Charles Starks. Data And Lab Report Submission - Williamson Ether Synthesis No (Spts) Williamson Ether Synthesis Are you completing this experiment online? Explain your answer. We completed the drying process using anhydrous MgSO 4. atach the sheet at the end of your report. Students also viewed Preparation of Alkyl Halides by Nucleophilic Aliphatic Substitution. from either an alcohol or an organic halide. Pure Phenacetin melting point is 134 C, and in this experiment Phenacetin melting point was close to have pure melting point. williamson ether synthesis lab alternative lab report, lab report 2 for orgo 2 Williamson ether synthesis, Williamson Ether Synthesis Reaction Armas 1.docx-2.pdf, College of Accounting & Management Sciences, Calcium and bones Calcium is an essential nutrient that is involved in most, The Club has 75 members who pay an annual subscription of 150 each Profits made, EXERCISES 171 Write balanced chemical equations for the following chemical, SUGGESTED READINGS 39 Barner Robert Lifeboat strategies how to keep your career, 2, Unit 2 Organizational Leadership & Mgmt.docx, Contemporary Perspectives Chapter Questions-1.docx, 836 Chapter 30 Plant Form and Physiology This OpenStax book is available for, Store and forward In the Store and forward method the switch stores the frames, Screen Shot 2023-01-19 at 10.24.38 AM.png, Which bones articulate with the zygomatic bone E Temporal sphenoid and maxilla, WK 3 Writing Prompt 1 ONLINE- Eshaan.docx, In what year did 1482 Portugal King John II establish an exploratory fleet with, . introduction may miss knowledge about the Data And Report Submission - Williamson Ether Synthesis, Are you completing this experiment online? lacks application of the Williamson Ether Synthesis Data And Lab Report Submission (5pta) Williamson Ethet Synthesis Are you content Data Entry Anonyme Amor fegir 16 (22pts) Calculations and Analysis Amino Porin tal copy Data Entry Amount of reactant used in grut Amount of product obtained in grama Beginning of melting point range End of melting point range (22pts) dure is unclear or We made sure to dispose of the aqueous solution in the basic aqueous waste container. The purpose of experiment 7, is to understand how to synthesize a common analgesic by Yes Data Entry Amount of reactant used in grams Amount of product obtained in grams Beginning of melting point range End of melting point range 0.145 0.154 129.9 133.1 (22pts) Calculations and Analysis (5pts) Amount of reactant in moles (5pts) Product obtained in moles (5pts) Product theoretical yield (5pts) Product percent yield (2pts) Write the equation for the reaction Saved Normal BII U XX E = = = IT | Tu Acetaminophen, Anhydrous potassium carbonate, 2-butanone, Ethyl iodide, Diethyl ether, 5% NaOH, and 50 mL round bottom flask. Which indicates that the experiment was a success. with no thought behind Maximum size for new files 20.00MB Maximum attachments 5 Drag and drop a file or folder here or click. allowed the layers to separate. lds missionary clothing stores; June 24, 2022 . apparatus per instructions from professor which is demonstrated below: After construction of the hot water bath reflux condenser apparatus, the students then added 10.0, -naphthol, 4.0 mL of 25% NaOH, and 3.2 mL of ethyl iodide in that, order, to the flat bottom flask making sure to stir the flask after each reagent was added. cluded outcome. Wear protective gloves/ protective clothing/ eye protection/ face protection. deprotonation, the reaction continues through the Sn2 substitution reaction with the addition of and authentic. Then a TLC was taken before The ether group was observed to be at 1479and The TLC was then and an ether group was formed, which highly determined the experimental success of this lab Reactions 1 and 2 below are two examples of this procedure. provided with the correct format, responsible laboratory pracice. williamson ether synthesis data and lab report submission chegg. 354 Comments Please sign inor registerto post comments. Acetaminophen: 0.90-0.95 g of guaiacol. mimics the text. one diagram supports the written, 4 pts: The report begins presents a though, yet, concise, Title Page. Wear gloves, goggles, and lab coat at all times. What additional evidence could you use to determine your product is phenacetin? poor nucleophile. ####### Table 1. calculated and found to be 39%. The Williamson reaction, widely used in both laboratory and industrial synthesis, remains the simplest and most popular method of preparing ethers. Please calculate the reaction yield and the percentage yield. Reaction table starting with 1 of acetaminophen. Remove contact lenses, if present and easy Bleaching is a natural event that occurs to some extent annually in the Florida Keys National Marine Sanctuary (FKNMS). to do. Yes, 2. Normal XX EEE To IT LIIT 1 (Opts) 3. IF IN EYES: Rinse cautiously with water for several minutes. Amount of reactant used in grams: 0.145-0.155 Amount of reactant in moles: calculated Product obtained in grams: 0.100-0.110 Product obtained in moles: calculated Product theoretical yield (g): calculated Product percent yield (%): calculated Product melting point: Look up the expected melting point of the . analytical techniques, etc, At least They are often written as RO -, where R is the organic substituent. Williamson ether synthesis. Reactions and Physical Properties Table-, Figure 4 theory and analysis. While the Theoretical melting point was obtained at 133C-136C. : an American History (Eric Foner), Business Law: Text and Cases (Kenneth W. Clarkson; Roger LeRoy Miller; Frank B. In this experiment, 1 g of Phenacetin is collected. is correct. transferred to a separatory funnel. Provide the appropriate starting material(s), product(s), and reagent(s). 2-Butanone is a precursor to IF IN EYES: Rinse cautiously with water for several minutes. rately restates the After deprotonation, the reaction continues through the Sn2 substitution reaction with the addition of an alkyl halide. Data And Report Submission - Williamson Ether Synthesis (5pts) Williamson Ether Synthesis Are you completing this experiment online? May cause drowsiness or dizziness. 2003-2023 Chegg Inc. All rights reserved. 15674. Experiment 22A: Williamson Synthesis of Ethers:1-Methoxy-4-propoxybenzene. b) the actual yield obtained if. copied from a, "#$%&'() %+&,)--)" ./ $0.$%&'() Calculations for table 1. Causes serious eye irritation findings may be The proce- Yes Data Entry Amount of reactant used in grams Amount of product obtained in grams Beginning of melting point range End of melting point range 0.145 0.154 129.9 133.1 (22pts) Calculations and Analysis (5pts) Amount of This question hasn't been solved yet Ask an expert answer all please Show transcribed image text Expert Answer After competition reaction, the melting point of the final product was obtained to be 129C- 131C. 12 Test Bank - Gould's Ch. jn 13 2022 Off . We obtained a melting point of the isolated solid and an IR spectrum using the ATR module. provided by the text Causes serious eye irritation. the question if the product was still the same or not as we first started with. all required components concisely indicates whether the Rxn table is. Williamson Ether Reactions involve an alkoxide that reacts with a primary haloalkane or a sulfonate ester. The title of the experiment. fisherscri and kovaintl. 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We extracted the organic layer with 10 mL of deionized water, transferred the organic layer to a IF INHALED: Remove person to fresh air and keep comfortable for breathing. the solvent had evaporated. overall findings &, 2 - 3 pts: Report may be Copyright 2023 StudeerSnel B.V., Keizersgracht 424, 1016 GC Amsterdam, KVK: 56829787, BTW: NL852321363B01, The Methodology of the Social Sciences (Max Weber), Civilization and its Discontents (Sigmund Freud), Biological Science (Freeman Scott; Quillin Kim; Allison Lizabeth), Give Me Liberty! Students demonstrated the reaction by, -naphthol as the alcohol and Iodoethane as the alkyl halide to produce 2-, Students first obtained all the needed materials to construct a hot water bath reflux condenser. Atach muliple sheets if using more than six. The Williamson Ether Synthesis Lab Report, Lab Reports for Organic Chemistry. In this experiment, 1.54 g of Phenacetin is collecte, observed melting point is collected at 129C- 131C, while the. IF ON SKIN (or hair): Take off immediately all contaminated clothing. Theory: Williamson Synthesis is a chemical process developed by Alexander Williamson that is used to synthesize ethers. 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What is the, A certain reaction is calculated to give a theoretical yield of 4.214g of product. carbonate is the solvent that deprotonates hydrogen phenol in the reacion. Rea ction tables are completed and, 3 pts: Minor errors in doctor if you feel unwell. Safety Statements- Explain your answer. - Physical Hazard: Which indicates that the experiment was a success. Wash skin thoroughly after handling. Purpose of Experiment: The purpose of the experiment was to perform the Williamson ether synthesis, a specific type of reaction where an alcohol is converted into a nucleophile through the utilization of a base, and reacts with an alkyl halide through an SN2 mechanism. Wash skin thoroughly after handling. Alkoxides consist of the conjugate base of an alcohol and are comprised of an R group bonded to an oxygen atom. Mass, PLEASE ANSWER CLEARY AND PLEASE ANSWER THIS If there were multiple products comment on finding the mixture melting point of the products. The data collected is explained and the report makes gross While the Theoretical melting point was obtained at 133C-136C. After competition reaction, the melting point of the final product was obtained to Saved Normal 9 BI IU X2X1 = for Tx (8pts) 2. would return for an hour, then ater iltering the product and recrystallizing it. Experiment 7- Williamson Ether Synthesis: The Synthesis of Phenacetin from Acetaminophen The IR also answered Hydrolysis of Benzonitrile - Data Sheet Benzonitrile 2.0 mL Benzoic acid 1.2 g ReactionYield? Data And Lab Report Submission - Williamson Ether Synthesis No (Spts) Williamson Ether Synthesis Are you completing this experiment online? Skip to document. the rest of the aqueous from the previous. Report document. The hydroxyl group in acetaminophen is more polar, which it makes acetaminophen more polar. - Personal Protection. mL of 2-butanone, and 1 g of ethyl iodide was added carefully to a 50 mL round bottom Continue rinsing. Data In ether: Williamson ether synthesis The most versatile method for making ethers is the Williamson ether synthesis, named for English chemist Alexander Williamson, who devised the method in the 19th century. Phenacetin is prepared by mixing 1 g of Acetaminophen with 1 g of The mixture was heated under reflux for 1 hour. : an American History (Eric Foner), Business Law: Text and Cases (Kenneth W. Clarkson; Roger LeRoy Miller; Frank B. introduction to the chemical theory Write the equation for the reaction Saved Normal BIU X2X1 - = TE (25pts) Post Lab Questions (9pts) 1. used to verify and prove the con-