He retired at the largest pension in federal history. The reason that it isnt used is because the medical community ignores evidence-based medicine principles. He pushes fluvoxamine, an anti-depression drug which despite doing very well in covid treatment studies has been strangely neglected. Steve Kirsch is a high-tech serial entrepreneur based in Silicon Valley. Skirsch.io traffic volume is 1,957 unique daily visitors and their 3,914 pageviews. Every earlier study of fluvoxamine (such as observational studies) showed it work and the mechanism had been shown. (PDF) Kaplan Textbook of Psychiatry JL copy - Academia.edu - Share research Medicine today isnt about saving your life. After several failed attempts to stop the progression of his disease, he designed his own protocol for chemotherapy and doctor-shopped to find an oncologist who would give it to him. Weve known it works since August 24, 2020. Medicine has been transformed to doing whatever the NIH/FDA says, regardless of how many lives will be lost. If the drug is started right after symptoms, weve seen 100% prevention in hospitalization. But fear of trying something new prevents any doctor from giving this drug a try. Thats why they didnt change their recommendation when the Phase 3 trial was published in Lancet. So there were too few events in the placebo group and they werent recruiting fast enough. CETF funded David Boulware's trials on hydroxychloroquine and the Phase 2 and Phase 3 fluvoxamine trials, among many other research projects. NIH and WHO refuse to acknowledge it works since it will cause vaccine hesitancy if it is known that there is a drug that turns COVID into a mild disease. The medical community doesnt care about saving lives. The results would, eventually, set Kirsch on a collision course with the scientific establishment. On Dr. Drew, he told a story about a friends daughter who had to get an abortion because of damage caused by the shot. My website www.skirsch.io has tons of info on fluvoxamine with all the links. It was recommended back in January 2021 by a key opinion leader (KOL) panel to be used, but it took a year for the KOL meeting notes to be published because they were rejected by 10 journals. In California, Silicon Valley tech entrepreneur Steve Kirsch was also thinking about the pandemic. So check the side-effects list to be familiar with which side-effects are associated with which drug so if you have a side-effect, youll know which drug to reduce or eliminate. 12:45 AM . The data we have today with just 2 clinical trials (RCT and confirmatory RWE) is compelling. Fluvoxamine has a systematic review and meta-analysis published in a top medical journal. Almost 2.5 million people signed up to Dr. B with the promise of getting leftover vaccines. P-value was 10^-14 on that study (done by Dr. PDF Fluvoxamine - The backstory Dosage there is 30mg once a day. Is that really true? ICER: Incriminating evidence - Steve Kirsch's newsletter - Substack When was the last time you saw a phase 3 fail where there was a 100% effect size in both an RCT and RWE study along with 4 independent observational trials all showing a positive effect, and there is clear mechanism of action where there is less than a 1% chance that it is not working (the SSRI's ordered their impact based on their Sigma activation which is 1 in 120 options), and where in every single case we are aware of the patient taking the drug reversed to normal in an average of 3 days? Both of them encouraged anyone reading this article to get vaccinated. [NIH] doesnt want any of these treatments. The agency quickly slapped down the comments from Kirsch, a tech mogul with a fortune once estimated at $230 million, even as the claims triggered a flurry of false social-media posts attributing. One of the drugs, Fluvoxamine, showed a 30 . CETF funded David Boulware's trials on hydroxychloroquine and the Phase 2 and Phase 3 fluvoxamine trials, among many other research projects. I took it myself at that dosage and noticed zero side effects. Fluvoxamine: The evidence - Steve Kirsch Home page He has a history of giving away some of his millions to good causes, and when COVID-19 began. Its whether Merck can make a killing that matters. Here is the latest version. Former Silicon Valley tech executive Steve Kirsch, a philanthropist and Substack author who created the COVID-19 Early Treatment Fund (CETF) to fund researchers working on repurposed drugs, including fluvoxamine, which reduces death from COVID by a factor of 12. 21. Or just depression about the vaccine mandates? Pennsylvania Senator Doug Mastriano Hosts Expert Panel on Medical The anecdotal data of 100% success rates is further icing on the cake. This is what the Seftel trial at Golden Gate fields used. Since FLV is a safe drug, it should have been widely discussed with patients that there is virtually no downside and a huge reduction in hospitalization if the drug is given early. 47).. Always be self aware when using fluvoxamine. Steve wanted to say, Look, Ive got all these famous [infectious disease] docs and researchers, and they all say give fluvoxamine a chance, Judith Feinberg, one of the former CETF advisory board members and vice chair of research at the West Virginia University School of Medicine, told me. Steve Kirsch: Vaccine Killing Millions, Treatments, VAERS, 5-Month Death Signal, Mystery Clots Embed 7.76K 31 'This Has Cost Millions Of Lives': Steve Kirsch On Suppression Of Repurposed Drugs And A Spike In Deaths 5 Months After Vaccine Rollout By Jan Jekielek American Thought Leaders / The Epoch Times November 24, 2022 Show more Or just depression about the vaccine mandates? But as Kirsch has clashed with the experts he initially surrounded himself with, hes grown increasingly close to others who share his perspectives on vaccineswho have, in turn, provided a large and receptive audience to his claims about a fluvoxamine conspiracy. Once the Phase 2 result came out, it should have been embraced by doctors. The track management was so impressed, they asked for prescriptions. Still, in the moment, his question threw me, and I stuttered. If you ask your doctor for any evidence that fluvoxamine doesnt work or is harmful (like a DB-RCT which is the only thing they trust), they will show you nothing. In severe cases, it takes longer. With cases spiking, the Los Angeles area banned gatherings. 1. During our first conversation, which turned into a multi-hour Zoom session, Kirsch paced through the rooms of his cavernous house with his phone held at chest level, rarely looking down at the camera. But they dont want their names used. Instead, it erodes confidence in our government to provide timely advice that is in the public interest. Author Affiliations Article Information. Steve Kirsch cut the check, which allowed Dr. Lenze to finish recruiting the 152 patients he needed for his trial. You can experience serious side effects if you do not pay attention to interactions such as if you are currently on another SSRI of a different type. . So much for evidence-based medicine. At the beginning of the COVID-19 pandemic, Steve Kirsch created the COVID-19 Early Treatment Fund (CETF) to finance trials of off-patent drugs in an attempt to find a potent treatment that had been staring us in the face. The drug was widely prescribed as a covid treatment for much of 2020, based on anecdotes and flawed studies. Also, for people who cant tolerate fluvoxamine for whatever reason (nausea, jittery, etc), this is the alternative. 90,000 people will die in the next 3 weeks alone if we continue to ignore this drug that has caused no harm. Get your prescription in advance of getting COVID. His foundation shifted focus to one goalcuring Steve Kirschby supporting one of the few scientists looking at the disease. Hes refused to accept the results of a hydroxychloroquine trial that showed the drug had no value in treating covid, for instance, instead blaming investigators for poor study design and statistical errors. Both drugs have compelling data that is hard to explain if the drug doesn't work. Nov 12: Steve Kirsch gives talk on CETF to HarvardBusiness School hosted by Dr. Seftel Nov 13:Mass COVID outbreak at GGF is now publiclyknown Nov 16: Seftel, the track physician at GGF, startsFLV . You can experience serious side effects if you do not pay attention to interactions such as if you are currently on another SSRI of a different type. Were having trouble saving your preferences. One user reported dilated pupils and increased heart rate (which could be nerves about the dilated pupils). Added to FLCCC protocols and Fareed-Tyson protocol among others. . Steve angrily decried this development as more evidence of FDA corruption. Steve Kirsch and the Seduction of Simplicity - McGill University It was not compatible with his position as CEO to continue taking a very public stance on the vaccines, Richard Char, M10s general counsel, told me. TV NEWS : Search Captions. Borrow Broadcasts : TV Archive : Internet No one has been able to come up with an example where phase 2 + this level of evidence resulted in a failure of Phase 3. This drug can save your life but you have to ask for it! How can we get fluvoxamine? NIH is still unsure whether fluvoxamine should be used to treat COVID (article I did after the TOGETHER trial). Fluvoxamine: Finding a possible early treatment for COVID-19 in a 40 Steve Kirsch - Wikipedia If you start later, doctors use higher dosages and compliance becomes a bigger problem. Steve Kirsch was extremely helpful early on in the pandemic, stepping up to fund early treatment trials when the US government would not fund such studies, Boulware told me in an email. It is an amazing drug and is a very simple safe way to avoid long-haul COVID symptoms. Seftel was able to duplicate the 100% protection from hospitalization and death in the treatment group, vs. a 12.5% hospitalization/death rate for the No treatment group. The sooner you start, the better the outcomes. Online Status. While Fauci was crafting national pandemic policies, Fauci's wife [Christine Grady, Chief Bioethicist, NIH] was back stopping [them]." Report coming soon. Its really, really common for a small effect, something that looks exciting, to be a statistical fluke when you look at a larger population. The documents in the data room discuss all eight (you'll need access to the restricted area to see the presentation on all 8). With covid, 80% of your patient population does just peachy with no treatment at all, just a little bed rest and fluid. It was 25 years ago yesterday that Andrew Wakefield launched the modern iteration of the antivaccine movement.In doing so, he laid down a template that antivax quacks today still follow. This looks ominous, but it harmless. Zero. I am not aware of a single case where taking the made things worse, e.g., person was doing fine BEFORE the drug and symptoms worsened after taking the drug. Kirsch is a serial entrepreneur who has spent decades pitching the next big thing, whether optical mice (Mouse Systems), document processing (FrameMaker), search engines (Infoseek), digital security (OneID), or e-commerce (Propel Software). He was recently featured on 60 Minutes which highlighted his . What has alarmed many of the scientists associated with CETF, though, are Kirschs reactions to the work hes fundedboth successes and failures. SSRI Antidepressant Fluvoxamine May Be Effective Early Treatments for Fluvoxamine is an inexpensive drug that has been in use for 37 years and has been used by an estimated 10 million people. Im sorry to sound so cynical. Less than a week later, David Seftel read about the Lenze trial, and ignored the JAMA advice. They all promised me when fluvoxamine passed Phase 3 trials, nearly everyone would use it. Medicine today isnt about saving your life. CETF founder Steve Kirsch accepted an invitation to discuss the findings on a weekly . Late in the session, minutes before this impromptu video wrap up, Tip o' Spear Steve Kirsch addressed the panel and revealed that the FDA had just shot down Fluvoxamine as an approved COVID treatment. Fluvoxamine data for COVID-19 Treatment - COVID-19 Early Treatment Fund Generally, at 50mg BID x 14, it is very tolerable as long as the patient is instructed to lay off the caffeine. That is when the phase 2 results were published. To date, the #1 drug with the most evidence to make a significant difference, without any doubt, is fluvoxamine. Other drugs in this class include Prozac (fluoxetine), Zoloft (sertraline) and Paxil (paroxetine). That receptor also helps regulate the body's . NIH doesnt want you to get the drug since it would compete with Molnupiravir, so fluvoxamine will never make the NIH guidelines. Debunking Steve Kirsch's latest claims about covid vaccine deaths 9th International Congress on Psychopharmacology 5th International Symposium on Child and Adolescent Psychopharmacology This document is a collection of evidence that highlights the glaring errors in our pandemic response. There were no studies reported out so far where fluvoxamine made things worse or neutral. They were all given the drug soon after symptoms and the placebo group was pure in that they were not taking any COVID drugs. But even that didnt last long. There are 4 outpatient studies that have been done (2 at WashU (see Phase 2 trial results published in JAMA), one in Berkeley, CA by David Seftel, one in Brazil published in the Lancet, and one in-patient study done in Croatia. Now weve lost the high ground, Morris told me. My experience is very typical. Drug researchers at Washington University in St. Louis reached out to Kirsch looking for $67,000 to finish a very smallbut placebo-controlledtrial. Steve Kirsch On COVID Early Treatment and Censorship - YouTube Once the Phase 2 result came out, it should have been embraced by doctors. While combining the results of several well-designed trials can strengthen an argument or unearth patterns unseen in smaller samples, a meta-analysis is just the sum of its parts; any single well-done experiment is more useful than combining the results of several poorly done ones. He has a BS/MS in Electrical Engineering and Computer Science from MIT. As of November 13, fluvoxamine has been proven to work in every trial that has published results, including outpatient and inpatient studies. The 50mg BID dose was quite effective, but it has to be started early (as soon as symptoms start). The infectious disease scientists lied to me. He has made millions from these projects, even if they have not turned him into a household name. Dose escalation studies in lupus patients and in rheumatoid arthritis patients established that 800 mg per day for life and 1,200 mg per day for 6 weeks are extremely well-tolerated. Steve Kirsch (@stkirsch) / Twitter - Twitter. It's what's happening Fluvoxamine, created 37 years ago, is an inexpensive and widely available generic drug. This give another 50% of benefit. People are dying. Fluvoxamine: A Review of Its Mechanism of Action and Its Role - PubMed Fluvoxamine works on hospitalized patients too, but no US hospital will let you use it (sound familiar? The medical community doesnt care about saving lives. Summarizes the 5 observational studies, RCT, RWE, and some of the more interesting anecdotal data. At the end of May this year, Siliciano emailed the other advisors to say that Kirsch had gone off the deep end and he was cutting ties. Mar. Long haul. To protect M10 from my COVID-19 vaccination opinions, I will no longer post about my vaccination concerns here.. Steve Kirsch Home page Worst case, if we ignore all additional evidence so the average is a 60% pass rate. Those days are gone. Compulsive fiddling with your mask? This was shown to be very tolerable (no side effects in 99% of patients) and extremely effective (no hospitalizations and death if you start it ASAP after first symptoms). Over the next few years, millions of unvaccinated people are going to get covid; its vital to try to mitigate their suffering, as well as lessen pressure on the health care system. . In September, Kirsch emailed Morris asking him to estimate the maximum number of deaths caused by vaccines. The U of M's study focused on three common drugs: ivermectin, metformin, and fluvoxamine. I wanted to get the article out before my flight left. CETF was founded by entrepreneur and philanthropist Steve Kirsch, as a way to expedite the fight against COVID-19. I took it myself at that dosage and noticed zero side effects. There are other non-prescription things you should always have on hand. 1:49 Press - treatearly.org Since then, he has continued to promote fluvoxamine, along with ivermectin and hydroxychloroquine. See this Wall Street Journal op-ed. Fauci wants the vaccine to be the only option, Cliff Lane works for Fauci, and Cliff follows his orders. Steve Kirsch: NIH and WHO COVID-19 Treatment Guidelines Are Too Note that some of these articles are inaccurate. So why would we wait when lives are being lost? are all super cheap, effective, and available without a prescription. Get your prescription in advance of getting COVID. When you need to characterize me, you need to say that Steve Kirsch doesnt go with majority votes on interpreting data, he told me when I asked about his views on ivermectin, which he insists is a silver bullet against covid. Fluvoxamine has at least a 30% hospitalization and death benefit. Other SSRIs work as well, but fluvoxamine activates the Sigma-1 receptor the most of the SSRIs which is why it was chosen. After two weeks (since it was a tight knit community, everyone could see what was happening to the two groups), every track worker who got sick with COVID, demanded the drug. Flavio Cadegiani and Steve Kirsch's studies didn't make the cut. Seftel used a 50mg BID dosing for 14 days which was one third of the max dose used in the Lenze study. Think about it Molnupiravir has a 50% risk reduction whereas fluvxoamine is over 90%. Several other trials around the world are in the final stages, too. Its all about NIH saying it is OK. Medicine today is driven by government opinion, not science. As noted before, the repository has a link to the 1 hour serotonin lecture. Fluvoxamine may prevent serious illness in COVID-19 patients Expert Panel Discussion on COVID-19 and Medical Freedom The reason that it isnt used is because the medical community ignores evidence-based medicine principles. The drugs mechanisms of action were explained to the KOL panel which voted 2>1 in favor of fluvoxamine. Independent appraisal committee votes 11-2 that the evidence is not adequate to demonstrate a net health benefit for molnupiravir over symptomatic care alone; Paxlovid and fluvoxamine receive more favorable votes. Thats why they didnt even fund the fluvoxamine trial, he told me. They rejected the drug for insufficient evidence just like they always do for ivermectin. It's hard to ignore this lecture in explaining why the drug is so effective. Steve Kirsch: Vaccine Killing Millions, Treatments, VAERS, 5-Month If there is a better drug on the table today than fluvoxamine, the NIH panel should put that one on the guidelines. has tons of info on fluvoxamine with all the links. Part of TV News Archive. So far, doctors have failed to share his sense of urgency. My publicly shared concerns regarding the safety of the COVID-19 vaccines may have had a negative impact on my company, M10. In the second trial, it was shown to be 100% effective in long-haul COVID symptoms: None of the treated patients had any long-haul symptoms after 2 weeks compared to 60% of untreated patients having 1 or more of the 15 long-haul symptoms after two weeks, and 29% having 4 of more of the long haul symptoms after 2 weeks. Vaccine waitlist Dr. B collected data from millions. (The fund borrows its nonprofit status from the 501(c)(3) Rockefeller Philanthropy Advisors, which managed its money until it quit, according to the Daily Beast; neither organization is related to the Rockefeller Foundation, which supports Technology Review's reporting on covid.). Steve Kirsch: $25,000 to Anyone that Proves Fluvoxamine - TrialSiteNews Steve Kirsch is a Silicon Valley philanthropist. On his blog, Covid-19 Data Science, he has extensivelyand mercilesslyunpacked Kirschs evidence for the vaccine death claims. Personal life. The paramedics will think you are on drugs. . The differences are obvious to untrained eyes. Article about the rejection (Stat News) Article about the fluvoxamine rejection (The Verge) NIH is still unsure whether fluvoxamine should be used to treat COVID (article I did after the TOGETHER trial). Hes adept at debate, rapidly shifting the premise of a conversation to put the other person on the back foot. That was a lie. The ongoing battle between social-media companies and covid-19 misinformation pushersincluding US president Donald Trumpstepped up again this week thanks to a new viral video. Fluvoxamine as a potential treatment for Covid - The External Medicine 19 In addition, several . Hes also recently increased the number of Americans he claim have been killed by the vaccine from 25,0000, to 150,000, or even as many as 250,000 Americans. By Steve Kirsch in fluvoxamine Feb 14, 2021 The case for fluvoxamine for treating COVID-19 A very short op-ed arguing for using fluvoxamine against COVID. ICER, a non-profit known as the nations drug pricing watchdog, did a review of the evidence and determined that fluvoxamine evidence is superior to Molnupiravir. Hes spending his own money to do what he thinks is right. Is fluvoxamine helpful for patients with the coronavirus? Is it - Quora reach out to us at In other cases, stop cold turkey. . Most doctors wont use it until NIH greenlights it, no matter what the science says. Although there is evidence that fluvoxamine can prevent clinical worsening and the need for hospitalizations in outpatients with early covid-19, I have seen no good evidence that fluvoxamine is useful as a substitute for the vaccines, co-investigator Angela Reiersen wrote to me. Fluvoxamine is way better than Molnupiravir, but the NIH doesnt approve drugs on effectiveness. I've collected fluvoxamine evidence here for convenient access. Fluvoxamine, Proxalutamide, and Ivermectin: 100% success Steve Kirsch. Ivermectin has been falsely promoted as a covid treatmentbut for those who use the drug legitimately, seeing it become a piece of anti-vaccine misinformation is disconcerting. 95% confidence effect size is 75% or more. In-patient use. Sage Hana. All can merit a fluvoxamine prescription based on traditional diagnoses. In short, a lot of mumbo jumbo. vocus MisinformationKills. Online. If you cant lay off the java, then try fluoxetine (Prozac). I only know of a few doctors who prescribe this off-label, all with 100% success rates. Hes now outlived his initial prognosis by several years. . One of the first CETF grants was to investigate the antimalarial hydroxychloroquine. In fact, he was unwittingly the source for one of Kirschs figures. Drug interactions should be checked for. It is very important to educate doctors because most people rely on their doctors for advice. He started a new pseudonymous account, @VaccineTruth2, to continue broadcasting messages. Keeping this drug off the NIH Guidelines does nothing to reduce the death rate. After boosting unproven covid drugs and campaigning against vaccines, Steve Kirsch was abandoned by his team of scientific advisersand left out of a job. The 5 observational studies is icing on the cake. skirsch.io Steve Kirsch Home page (The ivermectin data are trash, Feinberg told me.